Epidemiology of Patients with Head and Neck and Esophagial Squamous Cell Carcinomas

Esophageal squamous cell carcinoma (ESCC) is disturbing because of its aggressive clinical path and high mortality rate. However, the prognosis of ESCC has been improving recently (Isono et al., 1991; Inoue, 1997; Ando et al., 2000; Takeshita et al., 1997). The prevalence rate of ESCC is varey according to gheographical situation. In the high prevalent regions such as north of China, northeastern of Caspian Littoral in Iran and Transkei in south Africa, the prevalence of ESCC is rainsed from 100 persons to 100000 persons (Tadataka et al., 1999). In order to detect esophageal SCC at an early stage, Lugol chromoendoscopy can visualize these dysplastic areas as Lugol-voiding lesions and has been widely used in high-risk populations because it is not ordinarily visible at routine endoscopy; (LVLs) (Mori et al., 1993; Shimizu et al., 2001). Lugol chromoendoscopy (LC), resulting in a dramatic increase in the number of superficial SCC detected (Sugimachi et al., 1988; Yokoyama et al., 1995; Dawsey et al., 1998). In order to detect of ESCC, at an earlier stage with Lugol staining, Lugol chromoendoscopy is an effective technique to detection of abnormalities.